Sunday, 8 September 2013

Faking and Fiddling Cancer Statistics

Studies on Cancer Treatments Fixed and Fiddled...(From the Horses Mouth!)


There's clear evidence that cancer treatment statistics are often highly questionable, if not downright fraudulent!




(Reuters) - A former researcher at Amgen Inc has found that many basic studies on cancer -- a high proportion of them from university labs -- are unreliable, with grim consequences for producing new medicines in the future.

"In cancer science, many 'discoveries' don't hold up". (Reuters)


During a decade as head of global cancer research at Amgen, C. Glenn Begley identified 53 "landmark" publications -- papers in top journals, from reputable labs -- for his team to reproduce. Begley sought to double-check the findings before trying to build on them for drug development.


Result: 47 of the 53 could not be replicated. He described his findings in a commentary piece published on Wednesday in the journal Nature.


"It was shocking," said Begley, now senior vice president of privately held biotechnology company TetraLogic, which develops cancer drugs. "These are the studies the pharmaceutical industry relies on to identify new targets for drug development. But if you're going to place a $1 million or $2 million or $5 million bet on an observation, you need to be sure it's true. As we tried to reproduce these papers we became convinced you can't take anything at face value."


THE BEST STORY
Other scientists worry that something less innocuous explains the lack of reproducibility.
Part way through his project to reproduce promising studies, Begley met for breakfast at a cancer conference with the lead scientist of one of the problematic studies.
"We went through the paper line by line, figure by figure," said Begley. "I explained that we re-did their experiment 50 times and never got their result. He said they'd done it six times and got this result once, but put it in the paper because it made the best story. It's very disillusioning."
Such selective publication is just one reason the scientific literature is peppered with incorrect results. Quote.

http://uk.reuters.com/article/2012/03/28/us-science-cancer-idUSBRE82R12P20120328

CAN YOU NOW SEE WHY "CANCER BREAKTHROUGH" STORIES ARE SO COMMON IN THE PRESS AND ON TV...ONLY TO THEN DISAPPEAR WITHOUT A TRACE.

Of course these attention grabbing stories have sold millions of newspapers and helped TV ad revenue.! And they remain a fabulous cash-cow for all involved, - including research facilities!

But... with Alternative Cancer Treatments...All Proof of Success Gets Mocked... and Thrown in the Trash Can! No matter how great the results might be.


Here's proof that people at the top deny any success and refuse to publish results and data from doctors employing alternative treatments that CONTRADICT their chosen paradigm, even if and when supported by somebody who has great status in medical circles.

Dr William Kelly was a dentist who cured his own pancreatic cancer, (usually terminal of course), and inspired by this, treated many others successfully with his system. When the results of his work were investigated, the results were staggering, with a very high success rate that far exceeded chemotherapy.


Kelley Treatment: The Cancer Treatment So Successful - Traditional Doctors SHUT It Down

New York City physician and cancer specialist Dr. Nick Gonzalez has had remarkable success treating some of the most difficult to treat cancer patients using his three-pronged nutritional approach; for example, pancreatic cancer patients treated by Dr. Gonzalez have survived for two to five years, as compared to similar patients receiving chemotherapy, who typically do not survive beyond 18 months

He didn't set out to treat cancer at first, let alone treat patients. His original plan was to be a basic science researcher at Sloan-Kettering, a teaching hospital for Cornell Medical College. He had a chance meeting with William Kelley, a controversial dentist who was one of the founders of nutritional typing. Dr. Kelley had been practicing alternative and nutritional approaches for over two decades at the time, leading him to begin a student project investigation of Kelley's work in the summer of 1981.

"I started going through his records and even though I was just a second year medical student, I could see right away there were cases that were extraordinary," he says. "Patients with appropriately diagnosed pancreatic cancer, metastatic breast cancer in the bone, metastatic colorectal cancer... who were alive 5, 10, 15 years later under Kelley's care with a nutritional approach." 


Dr Mercola http://articles.mercola.com/sites/articles/archive/2011/04/23/dr-nicholas-gonzalez-on-alternative-cancer-treatments.aspx








The Problem with Trials

The big problem with trials relating to alternative cancer treatments, is that the people ultimately carrying out the investigation are the very people who stand to lose billions if successful! On top of that, everything they stand for will be shown to be an epic failure.



If you wonder how mainstream medicine got so ignorant of the healthy healing power of proper nutrition, supplements, -  and dealing with the causes of disease, instead of just treating symptoms, read on.

This is a great article I recently read by Tony Isaacs which will explain to you briefly exactly how the medical system in this country (and other "civilized" countries) was corrupted by monied interests in the early 1900's and remains so today..

(NaturalNews) Three fateful actions dating back over 100 years ago ultimately led to today's mainstream model of medicine: Treating the body as a collection of parts instead of treating and nurturing the whole body; treating illness by managing symptoms with unnatural drug compounds; and ignoring and suppressing safer and more effective natural health and healing. As a result, millions of lives have been lost and many millions more have suffered needlessly.

How Mainstream medicine Lost the Plot...


More Corruption Exposed...


"Last week, Chinese security authorities reported that GSK executives admitted to funnelling bribes to Chinese doctors and officials through 700 travel agencies and consultancies over six years. The Guizhou man's experience illustrates the ubiquity of such malfeasance in China's healthcare system – and the widespread outrage that it's caused...."
http://www.guardian.co.uk/world/2013/jul/21/china-healthcare-industry-gsk



Admission of Failure: (Nature Journal)
Even the prestigious journal NATURE.COM admits to huge failings...

Some quotes from:

Drug development: Raise standards for preclinical cancer research


"Efforts over the past decade to characterize the genetic alterations in human cancers have led to a better understanding of molecular drivers of this complex set of diseases. Although we in the cancer field hoped that this would lead to more effective drugs, historically, our ability to translate cancer research to clinical success has been remarkably low...."

this low success rate is not sustainable or acceptable, and investigators must reassess their approach to translating discovery research into greater clinical success and impact."

"Many factors are responsible for the high failure rate, notwithstanding the inherently difficult nature of this disease. Certainly, the limitations of preclinical tools such as inadequate cancer-cell-line and mouse models2 make it difficult for even the best scientists working in optimal conditions to make a discovery that will ultimately have an impact in the clinic.

"Issues related to clinical-trial design — such as uncontrolled phase II studies, a reliance on standard criteria for evaluating tumour response and the challenges of selecting patients prospectively — also play a significant part in the dismal success rate."

"More troubling, some of the research has triggered a series of clinical studies — suggesting that many patients had subjected themselves to a trial of a regimen or agent that probably wouldn't work.
These results, although disturbing, do not mean that the entire system is flawed."

Well that's a relief!!

http://www.nature.com/nature/journal/v483/n7391/full/483531a.html (Full Nature article)

If you read the papers, you could be forgiven for imagining that Othodox cancer treatment was on the brink of a huge breakthrough. They have maintained this BIG LIE for decades. It guarantees funding for everyone concerned...including Universities. Yet the facts on the ground show a ver different story. The skills employed by the press release department  are remarkable, and worth every million spent.

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